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Search Results for " drug-linker conjugates for adc "

20

Compounds

Cat No. Product Name Synonyms Targets
T15098 Deruxtecan Others
Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402.
T18867 Val-Cit-PAB-MMAE
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat...
T17983 Fmoc-Val-Cit-PAB-MMAE Others
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC.
T16031 McMMAF Maleimidocaproyl monomethylauristatin F Microtubule Associated
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other prote...
T16899 SMCC-DM1 DM1-SMCC Others
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC).
T12573 Vipivotide tetraxetan PSMA-617 Others
Vipivotide tetraxetan (PSMA-617) is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM).
T4232 VCMMAE mc-vc-PAB-MMAE Microtubule Associated
VCMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity.
T11917 Lys-SMCC-DM1 Lys-Nε-MCC-DM1 Microtubule Associated
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1.
T18312 Mc-MMAE Maleimidocaproyl-monomethylauristatin E Microtubule Associated
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
T17731 CL2A-SN-38 Others
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific ant...
T17977 Fmoc-PEA
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
T17654 Boc-NH-C6-Br Others
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1].
T14746 Boc-NH-PEG4-CH2COOH PROTAC Linker
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1].
T18308 MC-Gly-Gly-Phe
MC-Gly-Gly-Phe is a cleavable linker. MC-Gly-Gly-Phe can be used for antibody-drug conjugates (ADC).
T18479 NH-bis(C1-Boc) Others
NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC).
T18870 Vc-MMAD Others
Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs t...
T9282 DBCO-C3-Acid DBCO-ACID Others
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates.
T3503 MC-Val-Cit-PABC-PNP Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate Others , AChR
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr...
T4286 Fmoc-Val-Ala-PAB-OH Fmoc-Val-Ala-PAB Others , AChR
Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-paclitaxel conjugates...
T18540 Phe-Lys(Trt)-PAB Others
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells.
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