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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15098 | Deruxtecan | Others | |
Deruxtecan is an ADC drug-linker conjugate consisting of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker for the synthesis of DS-8201 and U3-1402. | |||
T18867 | Val-Cit-PAB-MMAE | ||
Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. Val-Cit-PAB-MMAE contains the ADCs linker (peptide Val-Cit-PAB) and a potent tubulin inhibitor MMAE . MMAE a potent mitotic inhibitor by inhibiting tubulin polymerizat... | |||
T17983 | Fmoc-Val-Cit-PAB-MMAE | Others | |
Fmoc-Val-Cit-PAB-MMAE is consisted of the ADCs linker (Fmoc-Val-Cit-PAB) and potent tubulin inhibitor (MMAE). Fmoc-Val-Cit-PAB-MMAE is a drug-linker conjugate for ADC. | |||
T16031 | McMMAF | Maleimidocaproyl monomethylauristatin F | Microtubule Associated |
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other prote... | |||
T16899 | SMCC-DM1 | DM1-SMCC | Others |
SMCC-DM1 (DM1-SMCC) (DM1-SMCC) is a drug-linker conjugate which composed of a potent microtubule-disrupting agent DM1 and a linker SMCC to make antibody-drug conjugate (ADC). | |||
T12573 | Vipivotide tetraxetan | PSMA-617 | Others |
Vipivotide tetraxetan (PSMA-617) is a high potent inhibitor of prostate-specific membrane antigen (PSMA)(Ki of 0.37 nM). | |||
T4232 | VCMMAE | mc-vc-PAB-MMAE | Microtubule Associated |
VCMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity. | |||
T11917 | Lys-SMCC-DM1 | Lys-Nε-MCC-DM1 | Microtubule Associated |
DM1 is a tubulin inhibitor. Lys-SMCC-DM1 (Lys-Nε-MCC-DM1) is the active metabolite of DM1. | |||
T18312 | Mc-MMAE | Maleimidocaproyl-monomethylauristatin E | Microtubule Associated |
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor. | |||
T17731 | CL2A-SN-38 | Others | |
CL2A-SN-38 is a drug-linker conjugate consisting of SN-38, a potent DNA topoisomerase I inhibitor, and linker CL2A, for the manufacture of antibody drug conjugates (ADCs). CL2A-SN-38 provides significant and specific ant... | |||
T17977 | Fmoc-PEA | ||
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC). | |||
T17654 | Boc-NH-C6-Br | Others | |
Boc-NH-C6-Br is a cleavable linker used for antibody-drug conjugates (ADC)[1]. | |||
T14746 | Boc-NH-PEG4-CH2COOH | PROTAC Linker | |
Boc-NH-PEG4-CH2COOH is a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC)[1]. | |||
T18308 | MC-Gly-Gly-Phe | ||
MC-Gly-Gly-Phe is a cleavable linker. MC-Gly-Gly-Phe can be used for antibody-drug conjugates (ADC). | |||
T18479 | NH-bis(C1-Boc) | Others | |
NH-bis(C1-Boc)is a uncleavable linker. NH-bis can be used for antibody-drug conjugates (ADC). | |||
T18870 | Vc-MMAD | Others | |
Vc-MMAD, a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), combines the ADC linker Val-Cit (Valine-Citrulline) with the potent tubulin inhibitor MMAD. This compound leverages the targeting capability of ADCs t... | |||
T9282 | DBCO-C3-Acid | DBCO-ACID | Others |
DBCO acid 2 is a Click Chemistry intermidate used for antibody-drug conjugates. | |||
T3503 | MC-Val-Cit-PABC-PNP | Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate | Others , AChR |
MC-Val-Cit-PABC-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a pr... | |||
T4286 | Fmoc-Val-Ala-PAB-OH | Fmoc-Val-Ala-PAB | Others , AChR |
Fmoc-Val-Ala-PAB-OH (Fmoc-Val-Ala-PAB) is a useful linker for making Antibody-Drug-Conjugation (ADC) conjugate for targeting drug delivery. It is also utilized in the synthesis of RGD peptidomimetic-paclitaxel conjugates... | |||
T18540 | Phe-Lys(Trt)-PAB | Others | |
Phe-Lys(Trt)-PAB is a cathepsin-cleavable linker utilized in the development of antibody-drug conjugates (ADCs)[1], serving as a crucial component for facilitating the release of therapeutic agents within targeted cells. |